S-Matrix was incorporated in the State of California in 1985. The company started as a consulting service, applying statistical tools and methods to solve industrial research and development problems in a variety of industries, including Aerospace, Fine Chemicals, Semiconductor, Consumer Products, and Pharmaceuticals.

For the past two decades S-Matrix has been developing advanced and innovative approaches to experimental design and multivariate data analysis according to Quality-by-Design principles, and incorporating these approaches into its Fusion AE expert-system software product suite. Fusion AE supports full 21 CFR 11 compliance and offers a built-in workflow management system with full user permissions and authorities control and e-review/e-approve workflow control.

S-Matrix’s strategic business alliances with international Pharmaceutical, Analytical Instrument, and Process Equipment companies enable S-Matrix to rapidly automate targeted R&D experimentation applications within the expert-system framework of its innovative Quality-by-Design software platform.